Remove seeds and peel and cut honeydew into one inch cubes. It should be approximately 4 cups of honeydew pieces.
Blend honeydew pieces in a blender on high until liquefied. Depending on the type of blender and ripeness of the honeydew, the mixture may need to be strained to remove larger chunks. You should have approximately 2 cups of honeydew puree.
Add tequila, lime juice, basil leaves, and cayenne to the blender and blend until basil leaves are pureed and everything is well combined. Taste the mixture and adjust the seasoning as desired.
Run a lime wedge around the edge of each glass to wet it and then dip all the edges of the glass in Tajin Classico seasoning to coat the rim.
Fill prepared glasses with ice and pour margarita mixture over the ice. Garnish with a fresh lime wheel and fresh basil leaf.
A super-ripe honeydew will make blending easier and make a sweeter taste to your margarita. A ripe honeydew will have more of a yellow rind that is smooth and slightly soft when pressed.
Substitutions and Variations
Lime juice - Fresh of bottled lime juice can be used for this drink.
Tajin Classico - Tajin Classico is a chili lime seasoning that goes really well with fruit and is perfect to rim the glasses of these spicy margaritas. Salt can also be used to rim the glasses if desired.
Basil - The fresh basil leaves in this recipe add a subtle freshness to the honeydew puree that also helps to balance out the cayenne pepper. They also make a beautiful garnish to the drink! If needed, they can be omitted.
Cayenne pepper - This is what makes this margarita spicy and can be adjusted or omitted, as desired.
Tequila - Blanco or silver tequila is best for margaritas. It's only aged up to 60 days so the flavor is more pure and mixes well into margaritas.
Not spicy - Omit the cayenne pepper and Tajin rim for a less spicy version of this cocktail.
Non-alcoholic - Omit the tequila and after blending all of the ingredients stir in 2 cups of club soda or lemon lime soda before serving.
Make Ahead and Storage Instructions
These honeydew spicy margaritas can be made up to 12 hours ahead of time and stored in airtight container in the refrigerator. At serving time, prepare the tajin rim on the glasses, fill with ice and pour the mix over the top.